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ChM. Dr. Kuan Shiong Khoo

BSc, PhD, MRSC

Algae Bioseparation Research, Department of Chemical Engineering and Materials Science, Yuan Ze University, Taoyuan, Taiwan.

Email: kuanshiong.khoo@hotmail.com or kuanshiong.khoo@saturn.yzu.edu.tw

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Biography

ChM. Dr. Kuan Shiong Khoo is an Assistant Professor in Department of Chemical Engineering and Materials Science at Yuan Ze University, Taiwan. Khoo’s PhD research focuses on the downstream processing of bioactive compounds such as proteins, lipids and carotenoids (i.e. astaxanthin, lutein and fucoxanthin) from microalgae using various extraction technologies such as liquid biphasic system, assisted-liquid biphasic system and ionic liquids technologies. His research interest also involves in microalgae-bacteria consortium for food waste management, wastewater treatment and volatile organic compound bioremediation, algae-based biofuels, and bioplastics, incorporation of Internet-of-things (IoT) and machine learning into microalgae biorefinery.

He obtained his bachelor’s degree (Applied Chemistry) with a major of Sustainable Chemistry at Universiti Teknologi PETRONAS, Malaysia from 2015 to 2018. He has successfully obtained his PhD in Chemical and Environmental Engineering (CEE) at University of Nottingham, Malaysia within two years’ time after obtaining his bachelor’s degree at Universiti Teknologi PETRONAS. During his postgraduate study, he has received some prestigious awards and achievements, including the Best Presenter Award Postgraduate Colloquium for Environmental Research (POCER) 2019, Top 15 Finalists YSN-ASM CHRYSALIS AWARD 2021 and University of Nottingham Malaysia Postgraduate Award Prize 2020/21.

He has published over 150+ journal articles (90% are ranked in Q1 journals) during his postgraduate careers (2019 – 2021) and his current h-index is 50 and i10-index is 150 with 9000+ citations in the research field of microalgae biotechnology. His is as an active reviewer in various high impact journals including Chemosphere, Bioresource Technology, Journal of Environmental Chemical Engineering, Environmental Research, Bioresource Technology, Science of the Total Environment, Fuel, Phytochemistry Reviews, Scientific Reports (Nature), Biocatalysis and Agricultural Biotechnology, Biochemical Engineering Journal, Clean Technologies and Environmental Policy and Bioengineered  He is currently an active Review Editorial in Frontier Sustainable Chemical Process Design and Circular Economy journal. He is also the guest managing editor for Bioengineered journal (Recent advances in bioprocess for sustainable high-valuable bioproducts: current and future perspective (POCER2022)). He is also served as managing and co-guest editor in some reputative journals that includes Chemosphere, Bioengineered and Energy NEXUS. He is the co-chair and organizer from UCSI University for the 6th Postgraduate Colloquium in Environmental Research (POCER 2022) conference: https://www.nottingham.edu.my/Conferences/POCER/index.aspx).

Research Areas Experience and Area of Interests

Upcycling of Food Waste with Microalgae Biotechnology

  • Upcycling food waste into alternative culture medium
  • Pretreatment and characterization of food waste
  • Biomass composition analysis after cultivating with food waste
  • Semi-batch cultivation using food waste for microalgae growth
Preparation of solid and liquid forms of food waste
Upcycling food waste as alternative culture medium for microalgae growth

Artificial Intelligent and Machine Learning for Prediction of Microalgae Biotechnology

(Credits to: Roy Chong Jun Wei for his contribution in using AI models for the classification of microalgae species)

Digitalised prediction of blue pigment content from Spirulina sp.

(Credits to: Roy Chong Jun Wei for his contribution in using AI models for the classification of microalgae species)

Real-time Monitoring of Microalgae Cultivation (IoT)

(Credit to Dr. Lim Hooi Ren for his contribution in using Internet of Things (IoT) with real time monitoring sensors for cultivating microalgae)

Microalgae Biotechnology: Upstream and Downstream Processing

Microalgae bioprocessing from upstream to downstream

  • Microalgae technology toward net-zero waste initatives: circular bioeconomy
  • Cultivation, harvesting and biorefinery engineering
  • Microalgae-bacterial consortium for bioenergy, CO2 sequestration and wastewater bioremediation
  • Incorporation of IoT-based continuous cultivation and extraction system
Cultivation of microalgae using food waste: a net zero waste concept
Different cultivation strategies of microalgae

Liquid Biphasic System Technology

  • Development of various phase forming components
  • Implementation of assisted technologies (ultrasound, bubble and electropermeabilization-assisted) with liquid biphasic technology
  • Extraction, purification and recovery technology
Electropermeabilization-LBF system
Integrated ultrasound-assisted liquid biphasic flotation for efficient extraction of astaxanthin from Haematococcus pluvialis
https://doi.org/10.1016/j.ultsonch.2020.105052
Extraction of fucoxanthin from Chaetoceros calcitrans by electropermeabilization-assisted liquid biphasic flotation system
https://doi.org/10.1016/j.chroma.2022.462915

Ionic Liquids Technology

  • Synthesis, characterization and application of ionic liquids
  • Dissolution of lignocellulosic material into cellulose processing
  • Cell permeabilization and extraction of microalgae high-value compounds
Series of alkyl carbamate ionic liquids
Scanning Electron Microscope of
Haematococcus pluvialis microalgae
Permeabilization of Haematococcus pluvialis and solid-liquid extraction of astaxanthin by CO2-based alkyl carbamate ionic liquids
https://doi.org/10.1016/j.cej.2021.128510
Permeabilization of Chlorella sorokiniana and extraction of lutein by distillable CO2-based alkyl carbamate ionic liquids
https://doi.org/10.1016/j.seppur.2020.117471
Bioprocessing of Chaetoceros calcitrans for the recovery of fucoxanthin using CO2-based alkyl carbamate ionic liquids
https://doi.org/10.1016/j.biortech.2020.124520

Professional Appointment

  • Assistant Professor, Department of Chemical Engineering and Materials Science, Yuan Ze University, Taiwan (2022 – current)
  • Visiting Professor, Chiang Mai University, Thailand, (2024- current)
  • Adjunct Assistant Professor, Chettinad Academy of Research and Education, India (2022 – current)
  • Visiting Professor, Centre for Research and Graduate Studies, University of Cyberjaya, Malaysia (2022 – 2023)
  • Member of Royal of Society of Chemistry (Membership number: 718422)
  • Member of IKM Institut Kimia Malaysia – Malaysian Institute of Chemistry (M/5822/9274/22)
  • Committee Member, International Bioprocess Society (2021 – current)
  • Postdoctoral Researcher Fellow, UCSI University, Malaysia (2021 – 2022)
  • Research Associate, Bioseparation Research Group, UNM (2019 – 2021)
  • Research Associate, Universiti Teknologi PETRONAS (2017 – 2018)